
I am a physician-scientist in the Division of Hematology/Oncology and an attending physician in the Genitourinary Medical Oncology Clinic at UCSF. Our lab is interested in multiple areas of cancer biology and translational oncology. Our current research projects include developing novel CAR T and radioimmunotherapies for prostate and bladder cancers (including identifying new therapeutic targets using transcriptomic and proteomic approaches), and understanding resistance mechanisms to antibody-drug conjugates and other surface-protein targeting modalities. In addition, we are interested in the role of CDK12 in regulating transcription and replication, and identifying new therapeutic approaches to treat this aggressive subtype of disease. I completed my postdoctoral research fellowship with Drs. Felix Feng and Alan Ashworth and my clinical training with Drs. Eric Small, Terence Friedlander and Chuck Ryan. I completed my PhD dissertation in the Biomedical Sciences program at UCSF with the late Dr. Zena Werb, and studied transcriptional regulation of metastasis and the tumor microenvironment.