Michael Evans, PhD

Professor
+1 415 514-1292

Michael Evans, PhD, is a Professor in Residence in the UCSF Department of Radiology and Biomedical Imaging. He is a chemical biologist with an interest in biomarker discovery with proteomics, nuclear medicine, theranostics, and molecular imaging. Dr. Evans earned a BA in Chemistry from St. Mary’s College of Maryland and he obtained his PhD in Organic Chemistry from The Scripps Research Institute (CA) under the supervision of Professor Benjamin Cravatt. This was followed by a postdoctoral fellowship in Molecular Imaging from the Memorial Sloan Kettering Cancer Center in New York under the supervision of Professors Charles Sawyers and Jason Lewis. In 2013, Dr. Evans accepted a faculty position at UCSF.

Dr. Evans has published over 80 peer-reviewed articles, 40 meeting abstracts, and is a co-inventor on 13 patents pending or issued. Dr. Evans also is the principle investigator or co-PI on several human trials focused on new strategies for imaging and treating tumors with radiopharmaceuticals. He is a scientific co-founder and previously served on the scientific advisory board of ORIC Pharmaceuticals, Inc. He is a co-founder of Therapaint, Inc, Honeybear Biosciences, and Hap10, Inc. Dr. Evans is a member of the American Chemical Society, the Society of Nuclear Medicine and Molecular Imaging, and the World Molecular Imaging Society. He has been invited nationally and internationally to lecture about his research. Has been recognized with numerous honors, including a 2013 Young Investigator Award from the Prostate Cancer Foundation, a Pathway to Independence Award from the National Cancer Institute, a 2017 Research Scholar Award from the American Chemical Society, the 2023 Roger Tsien Award for excellence in chemical biology from the World Molecular Imaging Society, the 2024 Sam Gambhir Trailblazer award from the Society of Nuclear Medicine and Molecular Imaging, and he was a 2020 inductee to the Council of Distinguished Investigators in the Academy of Radiology and Biomedical Imaging Research.

Expertise:
Chemical Biology, Positron emission tomography, Targeted Radioligand Therapy, Organic Chemistry, Cancer Biology,

Education and Training:
• Bachelor of Art: St. Mary’s College, St. Mary’s City, Maryland - Chemistry
• Doctor of Philosophy: The Scripps Research Institute, La Jolla, California - Organic Chemistry
• Postdoctoral Fellowship: Memorial Sloan Kettering Cancer Center, New York - Molecular Imaging

Honors and Awards
Sam Gambhir Trailblazer Award, Society of Nuclear Medicine and Molecular Imaging, 2024
Roger Tsien Award, World Molecular Imaging Society, 2023
Translational Science Grant, V Foundation, 2020-2023
Challenge Award, Prostate Cancer Foundation, 2020-2021
Council of Distinguished Investigators, The Academy for Radiology and Biomedical Imaging Research, 2020
Dean's Apple Award for Teaching, UCSF School of Pharmacy, 2020
Pilot Award, The LAM Foundation, 2019-2020
Research Scholar Award, American Cancer Society, 2017-2021
Discovery Award, American Brain Tumor Association, 2017-2018
Brain Tumor SPORE Developmental Research Project, UCSF, 2016-2018
Precision Imaging of Cancer and Therapy Pilot Award, Helen Diller Family Comprehensive Cancer Center, 2016-2017
Team Science Award, UCSF Academic Senate, 2016-2017
Idea Development Award, DOD Prostate Cancer Research Program, 2015-2017
Pilot Award, UCSF Academic Senate, 2014-2015
David H. Koch Young Investigator Award, Prostate Cancer Foundation, 2013-2016
Pathway to Independence Award, National Cancer Institute, 2012-2017
Research Grant, Imaging and Radiation Sciences Brigde Program, MSKCC, 2012-2014
Research Award, Brain Tumor Center of Memorial Sloan Kettering Cancer Center, 2011
Research Award, Imaging and Radiation Sciences Bridge Program, Memorial Sloan Kettering Cancer Center, 2011
R25 Fellowship, National Institutes of Health and Memorial Sloan Kettering Cancer Center, 2007-2010

Publications

Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET.

Clinical cancer research : an official journal of the American Association for Cancer Research

Wang S, Li J, Hua J, Su Y, Beckford-Vera DR, Zhao W, Jayaraman M, Huynh TL, Zhao N, Wang YH, Huang Y, Qin F, Shen S, Gioeli D, Dreicer R, Sriram R, Egusa EA, Chou J, Feng FY, Aggarwal R, Evans MJ, Seo Y, Liu B, Flavell RR, He J

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.

The British journal of radiology

Lux F, Tran VL, Thomas E, Dufort S, Rossetti F, Martini M, Truillet C, Doussineau T, Bort G, Denat F, Boschetti F, Angelovski G, Detappe A, Crémillieux Y, Mignet N, Doan BT, Larrat B, Meriaux S, Barbier E, Roux S, Fries P, Müller A, Abadjian MC, Anderson C, Canet-Soulas E, Bouziotis P, Barberi-Heyob M, Frochot C, Verry C, Balosso J, Evans M, Sidi-Boumedine J, Janier M, Butterworth K, McMahon S, Prise K, Aloy MT, Ardail D, Rodriguez-Lafrasse C, Porcel E, Lacombe S, Berbeco R, Allouch A, Perfettini JL, Chargari C, Deutsch E, Le Duc G, Tillement O

Imaging PD-L1 Expression with ImmunoPET.

Bioconjugate chemistry

Truillet C, Oh HLJ, Yeo SP, Lee CY, Huynh LT, Wei J, Parker MFL, Blakely C, Sevillano N, Wang YH, Shen YS, Olivas V, Jami KM, Moroz A, Jego B, Jaumain E, Fong L, Craik CS, Chang AJ, Bivona TG, Wang CI, Evans MJ