
Professor, Department of Anesthesia
+1 628 206-3251
Publications
A phase 1b dose escalation study of FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with enzalutamide (Enza) in patients with metastatic castration resistant prostate cancer (mCRPC)
Journal of Clinical Oncology
Development of CD46 Targeted Alpha Theranostics in Prostate Cancer using134Ce/225Ac-Macropa-PEG4-YS5
Theranostics
CD46-targeted theranostics for Positron Emission Tomography and 225Ac-radiopharmaceutical Therapy of Multiple Myeloma
Clin Cancer Res.
CD46 targeted 212Pb alpha particle radioimmunotherapy for prostate cancer treatment
J Exp. Clin. Cancer Res.
Evaluation of 134Ce/134La as a PET Imaging Theranostic Pair for 225 Ac a-Radiotherapeutics
J Nucl Med.
Phase 1a/1b study of FOR46, an antibody drug conjugate (ADC), targeting CD46 in metastatic castration-resistant prostate cancer (mCRPC)
Journal of Clinical Oncology
Phase 1a/1b study of FOR46, an antibody drug conjugate (ADC), targeting CD46 in metastatic castration-resistant prostate cancer (mCRPC)
Journal of Clinical Oncology
Enhanced Solid Tumor Recognition and T cell Stemness with SynNotch CAR Circuits
Science translational medicine
A first-in-human study of FOR46 in men with metastatic castration resistant prostate cancer (mCRPC)
Annals of Oncology.
Molecular imaging of prostate cancer targeting CD46 using immunoPET
Clinical Cancer Res
Potent activity of an anti-ICAM1 antibody-drug conjugate against multiple myeloma
Clinical Cancer Res
Quantitative (99m)Tc Labeling Kit for HYNIC-Conjugated Single Chain Antibody Fragments Targeting Malignant Mesothelioma
Bioconjug Chem.
Manipulation of cell-type selective antibody internalization by a guide-effector bispecific design
Mol Cancer Ther.
Modular Construction of Large Non-Immune Human Antibody Phage-Display Libraries from Variable Heavy and Light Chain Gene Cassettes
Methods Mol Biol.
Identification of Novel Macropinocytosing Human Antibodies by Phage Display and High-Content Analysis
Methods Enzymol.
Proteome-wide identification of novel ceramide-binding proteins by yeast surface cDNA display and deep sequencing
Mol Cell Proteomics.
Macropinocytosis exploitation by cancers and cancer therapy
Frontier Physiology
Combining phage and yeast cell surface antibody display to identify novel cell type-selective internalizing human monoclonal antibodies
Methods Mol Biol.
Identification of Posttranslational Modification-Dependent Protein Interactions Using Yeast Surface Displayed Human Proteome Libraries
Methods Mol Biol.
Identification of novel protein-ligand interactions by exon microarray analysis of yeast surface displayed cDNA library selection outputs
Methods Mol Biol.
Utilizing Yeast Surface Human Proteome Display Libraries to Identify Small Molecule-Protein Interactions
Methods Mol Biol.
An engineered cysteine-modified diabody for imaging activated leukocyte cell adhesion molecule (ALCAM)-positive tumors.
Molecular imaging and biology
Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas.
Cancer research
Construction of yeast surface-displayed cDNA libraries.
Methods in molecular biology (Clifton, N.J.)
Identification of protein/target molecule interactions using yeast surface-displayed cDNA libraries.
Methods in molecular biology (Clifton, N.J.)
Comprehensive analysis of yeast surface displayed cDNA library selection outputs by exon microarray to identify novel protein-ligand interactions.
Molecular & cellular proteomics : MCP
Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy.
Molecular therapy : the journal of the American Society of Gene Therapy
Identification of internalizing human single antibodies targeting brain tumor stem cells
Mol Cancer Ther.
Development of a highly stable and targetable nanoliposomal formulation of topotecan.
Journal of controlled release : official journal of the Controlled Release Society
Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single chain antibodies
Mol Cancer Ther
Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies.
Molecular immunology
Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells
Mol Cancer Ther
Explore Cell Type-Specific Internalizing Antibodies For Targeted siRNA Delivery
Brief Funct Genomic Proteomic
Interrogating yeast surface-displayed human proteome to identify small molecule-binding proteins
Mol Cell Proteomics
Construction and application of a yeast surface-displayed human cDNA library to identify post-translational modification-dependent protein-protein interactions
Mol Cell Proteomics
Identification of clinically significant tumor antigens by selecting phage antibody library on tumor cells in situ using laser capture microdissection
Mol Cell Proteomics
Applying phage antibodies to proteomics: selecting single chain Fv antibodies to antigens blotted on nitrocellulose.
Analytical biochemistry
Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex.
Science (New York, N.Y.)
Organizational change as human process, not technique.
NIDA research monograph
A transcribing RNA polymerase molecule survives DNA replication without aborting its growing RNA chain.
Proceedings of the National Academy of Sciences of the United States of America